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cancer-101-national-geographic

What is cancer, and how does it start? Find out how genetics play a role, which types of cancer are the most prevalent, and what is being done to fight this deadly disease.

Today cancer causes one in every seven deaths worldwide.

Our bodies contain trillions of highly specialized cells

and each carries genes responsible for regulating cell growth and division.

But when a genetic change disrupts this process

cells begin to grow and divide uncontrollably thereby becoming cancer.

The genetic changes that cause cancer usually happen in three types of genes.

Proto-oncogenes, which signal a cell to grow and divide.

Tumor suppressor genes, which signal a cell to stop dividing.

And DNA repair genes, which preserve and maintain genetic codes.

Changes in these genes lead to abnormal cell growth

resulting in masses of tissues called tumors.

Tumors may be benign, meaning that they remain in one area,

or malignant, which means that they are capable of spreading.

a malignant tumor's cells will eventually break off,

and begin forming tumors in other regions.

When this happens the cancer has become metastatic

Inherited traits may be behind some of the genetic changes

that lead to the formation of cancerous cells,

Such as excessive radiation from the sun, or chemicals in cigarette smoke.

In the United States today roughly one-third of all people

Of the over 100 different types of cancer

breast cancer is currently the most prevalent type,

But our ability to fight cancer is improving.

Since just the 1990s cancer mortality rates have dropped more than 26% in the US,

and more than two million lives have been saved.

As treatments and methods of early detection improve, and doctors, scientists, and the public

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Cancer 101 | National Geographic

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